Broadly there are four main areas of clinical indications for botuliunum toxin:

• Toxin effects on muscles - e.g. ophthalmology, neurology.
• Effects on glands - e.g. hyperhidrosis, submandibular gland, benign prostatic hypertrophy.
• Pain relief - e.g. prophylatic treatment of migraine.
• Dermatological indications - e.g. rosacea, certain types of psoriasis, facial inflammatory diseases and acne, potential for scar reduction, and wound healing - although the evidence base is not strong for some of these indications yet.